Impact of mirna in atherosclerosis

Author: wpwv

August undefined, 2024

Witrynascientific article published on 01 September 2024 WitrynaAtherosclerosis is closely related to vascular dysfunction and hypertension. Ojeoksan (OJS), originally recorded in an ancient Korean medicinal book named “Donguibogam”, is a well-known, blended herbal formula. This study was carried out to investigate the beneficial effects of OJS on atherosclerosis in vitro and in vivo. Western-diet-fed …

Impact of miR-200b and miR-495 variants on the risk of large …

Witryna19 sie 2024 · Atherosclerosis remains the leading cause of a broad spectrum of deadliest cardiovascular diseases. MicroRNA‐33 is a new therapeutic target for atherosclerosis due to its diverse functions. However, it remains a great challenge in clinical translation of nucleic acid‐based microRNA‐targeting therapeutics. … Witryna19 lut 2016 · The recent emergence of microRNAs (miRNAs) as important regulators of pathophysiological processes, such as cellular adhesion, proliferation, lipid uptake … cytokine closed system 320k

MicroRNAs as Therapeutic Targets and Clinical Biomarkers in …

WitrynaInhibition of miR-33 results in increased cholesterol efflux and HDL-cholesterol levels in mice. In this study we examined the effect of miR-33 inhibition in a mouse model of atherosclerosis and observed significant reduction in atherosclerotic plaque size. At the end of the study, gene expression in macrophages from the atherosclerotic plaques … Witryna18 gru 2013 · By using a technology called "locked nucleic acids," Jo and his colleagues tested the effects of blocking miR-712 in the body. When given to mice in the rapid atherosclerosis model, the anti-miR-712 drug inhibited the development of arterial blockages. Without the drug, plaques blocked an average of 80 percent of the … Witryna20 mar 2024 · Background: Atherosclerosis (AS) is a major risk factor for cardiovascular disease. microRNAs play a key role in gene regulation in the formation and … cytokine classification

RUN: The role of miRNAs in the diagnosis of stable atherosclerosis …

Impact of miRNA in Atherosclerosis (Q57822561) - wikidata.org

WitrynaBACKGROUND: Oxidative stress is a new risk factor for atherosclerosis. Increased oxidative stress in hemodialysis (HD) patients may arise from uremia-associated metabolic/humoral abnormalities and bi WitrynaDownload scientific diagram The screened miR-342-5p facilitated the apoptosis of HUVECs impaired by H2O2. (A) The heat map of top-30 upregulated miRNAs ranked … bing birthday candlesWitryna22 lip 2024 · The authors hypothesized that ACP5, as a direct target of lncRNA-H19, causes atherosclerosis by affecting cellular proliferation and apoptosis (Huang et al. 2024). Many studies have reported that lncRNA-H19 functions as a ceRNA to sponge its target miRNAs such as microRNA let-7 (Hsu et al. 2014; Sun et al. 2024b; Cao et al. … cytokine concentration翻译

"WitrynaThe let-7 miRNA family plays a key role in modulating inflammatory responses. Vascular smooth muscle cell (SMC) proliferation and endothelial cell (EC) dysfunction are critical in the pathogenesis of atherosclerosis, including in the setting of diabetes. Here we report that let-7 levels are decrease … " - Impact of mirna in atherosclerosis

Impact of mirna in atherosclerosis

IJMS Free Full-Text TMAO Upregulates Members of the miR …

Witryna17 gru 2024 · This study presents novel evidence linking miR-155 biology with the progression and regression of atherosclerosis. Herein, we have shown an inverse … Witryna13 maj 2024 · In addition, the effect of miR-100-5p on the SMAD7 expression was only evident upon combined treatment in HASMCs. Interestingly, the effect of miR-100-5p …

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WitrynaAtherosclerosis is a condition caused by lipid-induced inflammation of the vessel wall orchestrated by a complex interplay of various cell types, such as endothelial cells, smooth muscle cells, and macrophages. ... we outline the effects of miRNA-145, -126, and -155 in atherosclerosis in vivo. Downregulation of miR-145, which controls ... Witryna24 cze 2024 · The inhibition of miR-33 using pHLIP-directed macrophage targeting improves atherosclerosis regression by increasing collagen content and decreased …

Witryna14 kwi 2024 · It should be noted that miR-10b expression is altered in whole human arteries affected by atherosclerosis [37, 40]. Mir10b knockout mice were resistant to … WitrynaCorrigendum to: “Krüppel-like factor 14 inhibits atherosclerosis via mir-27a-mediated down-regulation of lipoprotein lipase expression in vivo” [Atherosclerosis Volume …

WitrynaHere, we aimed to screen the atherosclerosis-associated miRNAs and preliminarily investigate the potential regulatory mechanism of... Endothelial Cells, Atherosclerosis and Mesenchymal Cells ... WitrynaAtherosclerosis is a hallmark of cardiovascular disease, and lifestyle strongly impacts its onset and progression. Nutrients have been shown to regulate the miR-17/92 cluster, …

WitrynaMiRNA controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-γ, and plays the roles in endothelial cell (EC), vascular smooth …

Witryna21 kwi 2024 · MicroRNA dysregulation occurs in many human diseases, including atherosclerosis. Here, we examined the serum expression and clinical significance … cytokine conference 2022Witryna1 wrz 2014 · Atherosclerosis is a chronic, inflammatory disease of the arterial wall that underlies many of the common causes of cardiovascular morbidity and mortality, including myocardial infarction (MI), and cerebrovascular and peripheral vascular disease. Early pathological descriptions viewed atherosclerosis as an end-stage … bing birthday cards freeWitryna27 lip 2024 · These findings imply that miR-142-5p may plays a role in the development of atherosclerosis. Next, we tested the effect of miR-142-5p on the 3′-UTR of ABCA1 using luciferase reporter constructs and demonstrated that miR-142-5p dose-dependently reduced mouse and human ABCA1 3′-UTR activities (Figure S11A and … cytokine cancer immunotherapyWitrynaAtherosclerosis is a hallmark of cardiovascular disease, and lifestyle strongly impacts its onset and progression. Nutrients have been shown to regulate the miR-17/92 cluster, with a role in endothelial function and atherosclerosis. Choline, betaine, and L-carnitine, found in animal foods, are metabolized into trimethylamine (TMA) by the gut … cytokine conferenceWitryna9 maj 2024 · microRNAs (miRNAs) are implicated in the development of a wide range of diseases, including atherosclerosis, obesity, and diabetes (5–8).Among these miRNAs, aberrant let-7 expression is associated with diseases including liver and lung fibrosis and cancer (9,10).In the context of diabetes-associated atherosclerosis (DAA), previous … cytokine concentration in human bloodWitryna13 paź 2024 · They have potential regulatory effects on atherosclerosis and vascular endothelial injury by targeting miR-30d-3p-TP53RK and miR-140-3p-MKK6 axis and … bing birthday images freeWitryna1 wrz 2024 · Request PDF On Sep 1, 2024, Yao Lu and others published Impact of miRNA in Atherosclerosis Find, read and cite all the research you need on … bing birthday images men